Publications

  • A Coetzee, DR Hall, EJ Langenegger, M van de Vyver, M Conradie. Frontiers in Clinical Diabetes and Healthcare 4, 1266017

    This study examined the characteristics and outcomes associated with DKA during pregnancy.The study took place between 1 April 2020 and 1 October 2022. Pregnant women with DKA, admitted to Tygerberg Hospital's Obstetric Critical Care Unit (OCCU) were included. Maternal characteristics, precipitants of DKA, adverse events during treatment, and maternal-fetal outcomes were examined.

  • MCID Ankia CoetzeeID 1*, David R. HallID 2, Mari van de Vyver3. PLOS One 18 (6), e0282446

    South African women of childbearing age are disproportionally affected by obesity and at significant risk of Type 2 Diabetes Mellitus (T2DM). Unless pregnant, they do not readily undergo screening for T2DM. With a local focus on improved antenatal care, hyperglycemia is often first detected in pregnancy (HFDP). This may erroneously be attributed to Gestational Diabetes Mellitus (GDM) in all without considering T2DM. Glucose evaluation following pregnancy is essential for early detection and management of women with T2DM in whom persistent hyperglycemia is to be expected. Conventional testing with an oral glucose tolerance test (OGTT) is cumbersome, prompting investigation for alternate solutions.

  • J Rodriguez-Saldana. Springer Nature

    The Diabetes Textbook: Clinical Principles, Patient Management and Public Health Issues (2nd Edition) addresses diabetes from a comprehensive, multidisciplinary perspective. Its purpose is to integrate state-of-the-art information on diabetes from specialists in various disciplines,

  • A Coetzee, DR Hall, M van de Vyver, M Conradie

    Plos one 18 (6), e0282446

  • J Kesavadev, F Jawad, A Deeb, A Coetzee, MAJ Ansari, D Shrestha, …The Diabetes Textbook: Clinical Principles, Patient Management and Public … 10 2023

    In former times, type 2 diabetes (T2D) was considered a disease associated with disruptions in the functioning of the pancreas. Later on, a surfeit of evidence revealed a series of additional factors that contribute to this annihilating disease. The understanding of T2D has evolved from recognizing the duo of pancreatic β-cell failure with defective insulin secretion and insulin resistance (IR) to the triumvirate with the addition of hepatic gluconeogenesis.

  • P Sadhai, A Coetzee, M Conradie-Smit, CJ Greyling, R van Gruting, ...Frontiers in Endocrinology 14, 1120531

    Background Obesity is a rising trend globally and increases morbidity and mortality. Metabolic surgery and adequate weight loss decrease mortality but may worsen pre-existing nutrient deficiencies. Most data on pre-existing deficiencies in the population undergoing metabolic surgery is from the developed world, where an extensive micronutrient assessment is achievable.

  • A Coetzee. South African Family Practice 65 (2)

    The benefits of the newer antidiabetic agents available for managing type 2 diabetes mellitus (T2DM) remain indisputable, but many patients will require insulin therapy in the disease course. Given the limited access to newer antidiabetic agents, insulin remains a standard treatment modality in T2DM in South Africa. Early, multifactorial intervention remains ideal, but glucose, blood pressure and cholesterol values remain above target in many countries. Barriers to achieving glucose control in South Africa include the healthcare provider’s being unfamiliar with the practicalities of insulin administration, initiation and titration. This article highlights these gaps and offers pragmatic solutions to overcome them.

  • Retroperitoneoscopic adrenalectomy–introducing a new surgical technique in South Africa

    Posterior retroperitoneoscopic adrenalectomy (PRA) is purported to be superior to the laparoscopic transperitoneal approach (LA) in patients with a select spectrum of benign adrenal pathologies. Advantages attributed to the technique include minimal blood loss, shortened operative times, and decreased postoperative pain, explained anatomically by the direct access to the adrenal gland. Reduced workspace is a limitation.

  • AL Wilhelmina Conradie, Jenny Edge, Ankia Coetzee, Magda Conradie

    South African Journal of Surgery. 1 (61(1)), 1-6

  • R Bhikoo, M Conradie-Smit, G Van Wyk, E Du Plessis, J Cilliers, S Hugo, ...Journal of Endocrinology, Metabolism and Diabetes of South Africa 27 (1), 42-48

    Objective: To reflect on the diagnosis, management, obstacles to care and outcome of four patients who were admitted to Tygerberg Hospital, Cape Town, South Africa. The outcome of these cases that presented consecutively with DKA and COVID-19 between May and July 2020 are discussed, the presentation, management and long-term considerations with specific reference to DKA and COVID-19 are reviewed.